Description

1-(4-Methylphenyl)-6,7-Dimethoxy-1,2,3,4-Tetrahydroisoquinoline Hydrochloride is a high-purity, synthetic organic compound belonging to the tetrahydroisoquinoline class. This compound is a critical pharmaceutical intermediate and a valuable building block for medicinal chemistry research, enabling the development of novel therapeutic agents. It is primarily required by pharmaceutical manufacturers and contract research organizations (CROs) engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the production of active pharmaceutical ingredients (APIs) with potential central nervous system (CNS) activity.
• Medicinal Chemistry Research: Serves as a versatile scaffold for the design and synthesis of new chemical entities targeting various biological pathways.
• Alkaloid Analog Synthesis: Used in the preparation of synthetic analogs of naturally occurring isoquinoline alkaloids for biological evaluation.
• Chemical Reference Standard: Employed as a high-purity standard for analytical method development, validation, and quality control in pharmaceutical laboratories.
• Process Development & Scale-up: Supports route scouting and optimization studies for the efficient manufacturing of complex molecules.

Basic Information

Item	Detail
Product Name	1-(4-Methylphenyl)-6,7-Dimethoxy-1,2,3,4-Tetrahydroisoquinoline Hydrochloride
CAS No.	96315-82-1
Molecular Formula	C18H22ClNO2
Molecular Weight	319.83 g/mol
Synonyms	1-(p-Tolyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride; 6,7-Dimethoxy-1-(4-methylphenyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride; 1-(4-Methylphenyl)-6,7-dimethoxy-3,4-dihydroisoquinoline hydrochloride; 1-(p-Methylphenyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline HCl; 96315-82-1; Tetrahydroisoquinoline derivative hydrochloride
EINECS	Contact for details

Quality Control

Our 1-(4-Methylphenyl)-6,7-Dimethoxy-1,2,3,4-Tetrahydroisoquinoline Hydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to guarantee compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.