Description

Methyl 4,5-Dibromo-3-Hydroxythiophene-2-Carboxylate is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its unique dibrominated thiophene core with an ester and a hydroxyl group makes it a versatile precursor for constructing complex molecular architectures. This compound is primarily sought after by research institutions and industrial R&D departments engaged in the development of pharmaceuticals, agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in the development of molecules with thiophene-based heterocycles for various therapeutic areas.
• Agrochemical Research: Used as a building block in the discovery and synthesis of new-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the brominated thiophene moiety.
• Material Science Precursor: Serves as a monomer or intermediate in the production of conductive polymers, organic semiconductors, and other advanced electronic materials.
• Chemical Synthesis Reagent: Employed in organic chemistry research for Suzuki-Miyaura and other cross-coupling reactions, where the bromine atoms act as excellent leaving groups.
• Ligand and Catalyst Development: Utilized to create novel chelating ligands or organocatalysts due to the presence of the hydroxyl and ester functional groups.

Basic Information

Product Name	Methyl 4,5-Dibromo-3-Hydroxythiophene-2-Carboxylate
CAS No.	96232-71-2
Molecular Formula	C6H4Br2O3S
Molecular Weight	315.97 g/mol
Synonyms	Methyl 3-hydroxy-4,5-dibromothiophene-2-carboxylate; 4,5-Dibromo-3-hydroxythiophene-2-carboxylic acid methyl ester; 3-Hydroxy-4,5-dibromothiophene-2-carboxylic acid methyl ester; Methyl 4,5-dibromo-3-hydroxythiophene-2-carboxylate; 2-Carbomethoxy-4,5-dibromo-3-hydroxythiophene; 4,5-Dibromo-3-hydroxy-2-thiophenecarboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 4,5-Dibromo-3-Hydroxythiophene-2-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.