Description

Methyl 5-Chloro-3-Hydroxythiophene-2-Carboxylate is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. Its unique thiophene core, functionalized with chloro, hydroxyl, and ester groups, makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and other therapeutic small molecules.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging its bioactive thiophene scaffold.
• Material Science Research: Serves as a monomer or building block for developing conductive polymers, organic semiconductors, and advanced functional materials.
• Dye and Pigment Intermediate: Employed in the synthesis of specialized dyes and organic pigments due to its chromophoric thiophene structure.
• Chemical Research & Development: A valuable reagent for method development, catalysis studies, and exploring new synthetic pathways in academic and industrial R&D laboratories.

Basic Information

Product Name	Methyl 5-Chloro-3-Hydroxythiophene-2-Carboxylate
CAS No.	96232-69-8
Molecular Formula	C7H5ClO3S
Molecular Weight	204.63 g/mol
Synonyms	Methyl 5-chloro-3-hydroxythiophene-2-carboxylate; 5-Chloro-3-hydroxythiophene-2-carboxylic acid methyl ester; 2-Thiophenecarboxylic acid, 5-chloro-3-hydroxy-, methyl ester; Methyl 5-chloro-3-hydroxy-2-thiophenecarboxylate; 3-Hydroxy-5-chlorothiophene-2-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Every batch of Methyl 5-Chloro-3-Hydroxythiophene-2-Carboxylate is produced and tested under a strict quality management system. We ensure compliance with relevant industry standards for research and fine chemical intermediates. Comprehensive analytical testing, including HPLC, GC, and NMR, is performed to verify identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.