Description

Tri(Methyl) Phosphite-D9 is a deuterated isotopologue of trimethyl phosphite, where nine hydrogen atoms are replaced by deuterium, making it a valuable labeled compound for research and analytical applications. Its primary value lies in its utility as a stable, non-radioactive tracer and internal standard in mass spectrometry and NMR studies, providing enhanced signal resolution and accuracy. This high-purity specialty chemical is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly for mechanistic studies, metabolic pathway tracing, and the development of deuterated active pharmaceutical ingredients (APIs).

Application

• Internal Standard for Analytical Chemistry: Used in quantitative GC-MS and LC-MS analysis due to its distinct mass shift, ensuring precise measurement of non-deuterated analogs.
• NMR Spectroscopy Solvent & Reagent: Serves as a deuterated reagent or solvent component in nuclear magnetic resonance studies to eliminate interfering proton signals.
• Deuterated API Synthesis: A key building block in the research and development of deuterium-labeled pharmaceutical compounds, which can offer improved metabolic stability and pharmacokinetic profiles.
• Mechanistic Reaction Studies: Employed as a tracer to elucidate reaction pathways and intermediates in organophosphorus chemistry and catalysis.
• Agrochemical Research: Used in the development and analysis of novel deuterated pesticides and herbicides.
• Polymer Science: Acts as a specialty monomer or additive in the synthesis of advanced polymeric materials with tailored properties.

Basic Information

Product Name	Tri(Methyl) Phosphite-D9
CAS No.	96201-07-9
Molecular Formula	C3D9O3P
Molecular Weight	156.13 g/mol
Synonyms	Trimethyl Phosphite-D9; Phosphorous Acid, Tris(methyl-d3) Ester; Deuterated Trimethyl Phosphite; Tris(trideuteriomethyl) Phosphite; (CD3O)3P; TMOP-D9; TMP-D9
EINECS	Contact for details

Quality Control

Our Tri(Methyl) Phosphite-D9 is manufactured under strict quality protocols to ensure high isotopic and chemical purity, critical for sensitive analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as isotopic enrichment (D-atom %), chemical purity by NMR and GC, and impurity profiles. We adhere to cGMP principles where applicable, and our quality systems are designed to meet the stringent requirements of research and development laboratories.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C) under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation and moisture absorption. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Isotopic Purity (D-atom %)	≥ 98%
Chemical Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.