Description

n-Acetyl-(4S,5R)-4-Methyl 5-Phenyl-2-Oxazolidinone is a high-purity, chiral oxazolidinone derivative widely used as a versatile chiral auxiliary and building block in asymmetric synthesis. Its value lies in enabling the stereoselective construction of complex molecules, ensuring high enantiomeric purity in final products. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries developing active ingredients and advanced intermediates.

Application

• As a chiral auxiliary in Evans-type aldol reactions and other asymmetric carbon-carbon bond-forming processes.
• Key building block for the synthesis of enantiomerically pure pharmaceuticals, including β-lactam antibiotics and protease inhibitors.
• Intermediate in the research and development of agrochemicals requiring specific stereochemistry for biological activity.
• Used in academic and industrial R&D for methodological studies in organic and medicinal chemistry.
• Precursor for the synthesis of other custom chiral auxiliaries and ligands for catalysis.
• Production of advanced fine chemicals and specialty materials where stereochemical control is critical.

Basic Information

Product Name	n-Acetyl-(4S,5R)-4-Methyl 5-Phenyl-2-Oxazolidinone
CAS No.	96093-41-3
Molecular Formula	C₁₃H₁₅NO₃
Molecular Weight	233.26 g/mol
Synonyms	(4S,5R)-4-Methyl-5-phenyl-3-acetyl-2-oxazolidinone; (4S,5R)-N-Acetyl-4-methyl-5-phenyl-2-oxazolidinone; Evans Chiral Auxiliary Derivative; (4S,5R)-1-Acetyl-4-methyl-5-phenyl-2-imidazolidinone; Acetyl-(4S,5R)-4-methyl-5-phenyloxazolidin-2-one; N-Acetyl-(4S-cis)-4-methyl-5-phenyl-2-oxazolidinone
EINECS	Contact for details

Quality Control

Our n-Acetyl-(4S,5R)-4-Methyl 5-Phenyl-2-Oxazolidinone is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity suitable for sensitive asymmetric synthesis. Certificates of Analysis (COA) with full characterization data are provided to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.