Description

4-(Hydroxy-Diphenyl-Methyl)-Piperidine-1-Carboxylic Acid Benzyl Ester is a high-purity, advanced pharmaceutical intermediate with a defined stereochemical center. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise molecular architecture. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and fine chemical industries for developing new drug candidates and scaling up production processes.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel therapeutic agents, particularly for central nervous system (CNS) and analgesic applications.
• Organic Synthesis: Used in research-scale and pilot-scale reactions to introduce the piperidine-benzhydrol moiety into more complex molecular frameworks.
• Process Chemistry: Serves as a critical starting material or intermediate in the development and optimization of scalable API manufacturing routes.
• Chemical Reference Standard: Employed as a high-purity standard for analytical method development, validation, and quality control in pharmaceutical labs.
• Academic & Industrial R&D: Facilitates medicinal chemistry research for structure-activity relationship (SAR) studies and new compound library generation.

Basic Information

Product Name	4-(Hydroxy-Diphenyl-Methyl)-Piperidine-1-Carboxylic Acid Benzyl Ester
CAS No.	96067-93-5
Molecular Formula	C26H27NO3
Molecular Weight	401.50 g/mol
Synonyms	1-Benzyl 4-[(hydroxydiphenylmethyl)piperidine]-1-carboxylate; 1-Benzyl 4-(hydroxydiphenylmethyl)piperidine-1-carboxylate; 4-(Hydroxydiphenylmethyl)-1-piperidinecarboxylic Acid Benzyl Ester; 4-(α-Hydroxybenzhydryl)-1-piperidinecarboxylic Acid Benzyl Ester; Benzyl 4-(hydroxydiphenylmethyl)piperidine-1-carboxylate; 4-(Hydroxy-Diphenyl-Methyl)-Piperidine-1-Carboxylic Acid Benzyl Ester; 1-Carbobenzyloxy-4-(hydroxydiphenylmethyl)piperidine
EINECS	Contact for details

Quality Control

Our 4-(Hydroxy-Diphenyl-Methyl)-Piperidine-1-Carboxylic Acid Benzyl Ester is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.