Description

3-Methylbutyric-2,2-D2 Acid CAS NO 95927-02-9 is a deuterium-labeled isotopologue of 3-methylbutyric acid, a branched-chain fatty acid. This compound is a critical tool in advanced research and development, enabling precise metabolic and pharmacokinetic studies through mass spectrometry and NMR spectroscopy. It is primarily required by pharmaceutical, agrochemical, and academic research laboratories for use as an internal standard, tracer, or building block in the synthesis of labeled complex molecules.

Application

• As a stable isotope-labeled internal standard for the accurate quantification of 3-methylbutyric acid and related metabolites in biological samples via GC-MS or LC-MS.
• As a metabolic tracer in studies investigating fatty acid metabolism, insulin resistance, and energy homeostasis.
• As a key deuterated synthetic intermediate in the preparation of isotopically labeled pharmaceuticals, agrochemicals, and fragrances.
• For use in NMR spectroscopy as a probe to elucidate reaction mechanisms and molecular structures without signal interference from protons.
• In flavor and fragrance research to study the biogenesis and stability of flavor compounds.
• For diagnostic assay development, enhancing the precision and reliability of clinical tests for metabolic disorders.

Basic Information

Product Name	3-Methylbutyric-2,2-D2 Acid
CAS No.	95927-02-9
Molecular Formula	C5H8D2O2
Molecular Weight	104.15 g/mol
Synonyms	Isovaleric-2,2-d2 Acid; 3-Methylbutanoic-2,2-d2 Acid; (2,2-Dideuterio-3-methylbutyric) Acid; Deuterated Isovaleric Acid; 2,2-Dideutero-3-methylbutyric Acid; Isobutylcarboxylic-2,2-d2 Acid; 3-Methyl[2,2-2H2]butyric Acid
EINECS	Contact for details

Quality Control

Our 3-Methylbutyric-2,2-D2 Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR and mass spectrometry, to confirm isotopic enrichment, chemical purity, and structural identity. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. For long-term stability, storage at 2-8°C is recommended.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Isotopic Enrichment (MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.