Description

2-Methyl-D3-Propionic Acid is a deuterium-labeled isotopologue of isobutyric acid, where three hydrogen atoms are replaced by deuterium. This compound is a critical tool for analytical chemistry, enabling precise metabolic and pharmacokinetic studies through mass spectrometry and NMR. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors for use as an internal standard, tracer, or building block in the synthesis of labeled compounds.

Application

• Internal Standard for Mass Spectrometry (MS): Provides high-accuracy quantification in bioanalytical methods for drug metabolism and pharmacokinetics (DMPK) studies.
• Metabolic Pathway Tracer: Used in stable isotope labeling experiments to elucidate biochemical pathways in both pharmaceutical and agricultural research.
• NMR Spectroscopy: Serves as a valuable probe for structural analysis and reaction monitoring due to the distinct properties of deuterium.
• Synthetic Intermediate: Acts as a deuterated building block for the preparation of more complex labeled pharmaceuticals, agrochemicals, or organic materials.
• Quality Control & Method Development: Essential in analytical laboratories for developing and validating robust chromatographic and spectroscopic methods.

Basic Information

Product Name	2-Methyl-D3-Propionic Acid
CAS No.	95926-99-1
Molecular Formula	C4D3HO2
Molecular Weight	91.11 g/mol
Synonyms	(2H3)-2-Methylpropanoic Acid; Deuterated Isobutyric Acid; Isobutyric-2,2,2-d3 Acid; 2-Methylpropionic-2,2,2-d3 Acid; (2,2,2-2H3)Isobutyric Acid; Isobutyric Acid-d3; 2,2,2-Trideuterio-2-methylpropanoic Acid
EINECS	Contact for details

Quality Control

Every batch of 2-Methyl-D3-Propionic Acid is produced and analyzed under strict quality management protocols. We guarantee high chemical and isotopic purity, with comprehensive testing including assay, isotopic enrichment (D-content), and identification. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place at room temperature (15-25°C). Due to its nature as a strong acid/organic solvent and high volatility, keep away from heat, sparks, and open flame. Ensure containers are securely sealed when not in use to prevent evaporation and contamination.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (GC/HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98.0 atom % D
Chemical Purity (by GC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.