Description

Cyclopropyl-1-D1 Methyl-D3 Ketone is a high-purity, isotopically labeled ketone compound, specifically deuterated at key positions. This precise labeling is critical for applications requiring advanced analytical techniques and metabolic pathway elucidation. It is primarily utilized by researchers and developers in the pharmaceutical, agrochemical, and analytical chemistry sectors for use as a stable isotope-labeled intermediate or internal standard.

Application

• Pharmaceutical Research & Development: Serves as a key deuterated building block or intermediate in the synthesis of novel Active Pharmaceutical Ingredients (APIs) for drug discovery and development programs.
• Metabolic Studies & Pharmacokinetics: Used as a stable isotope-labeled internal standard in Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS) for accurate quantification and tracing of metabolites.
• Agrochemical Research: Employed in the synthesis of labeled agrochemicals to study environmental fate, degradation pathways, and residue analysis.
• Analytical Chemistry: Functions as a high-purity reference standard for method development and validation in sophisticated analytical laboratories.
• Mechanistic Organic Chemistry: Utilized in reaction mechanism studies, where deuterium labeling provides insights into kinetic isotope effects and reaction pathways.
• Material Science Research: Acts as a specialized precursor for developing novel organic materials with tailored properties.

Basic Information

Product Name	Cyclopropyl-1-D1 Methyl-D3 Ketone
CAS No.	95249-93-7
Molecular Formula	C5H4D4O
Molecular Weight	86.13 g/mol (for C5H4D4O)
Synonyms	Deuterated Cyclopropyl Methyl Ketone; (Methyl-d3)(cyclopropyl-1-d1)ketone; 1-Cyclopropyl-2,2,2-trideuterio-1-deuterioethanone; Cyclopropanecarboxylic-d acid, methyl-d3 ester; Ketone, cyclopropyl methyl-d4; d4-Cyclopropyl methyl ketone; Cyclopropyl(methyl-d3)ketone-1-d1
EINECS	Contact for details

Quality Control

Our Cyclopropyl-1-D1 Methyl-D3 Ketone is manufactured under strict quality systems to ensure batch-to-batch consistency and high isotopic purity. Each lot undergoes comprehensive analysis using techniques including NMR, GC-MS, and HPLC to confirm chemical identity, isotopic enrichment (D-atom %), and chemical purity. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. For long-term storage, keeping the container under an inert atmosphere (e.g., nitrogen or argon) in a freezer (e.g., -20°C) is recommended to maintain stability and isotopic integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR / NMR)	Conforms to structure
Purity (GC / HPLC)	≥ 98.0% (chemical purity)
Isotopic Purity (D-atom %)	≥ 98.0% (by MS)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.