Description

Methyl 4-Chloro-3-Hydroxy-5-Methoxythiophene-2-Carboxylate is a high-purity, multifunctional heterocyclic building block of significant importance in advanced organic synthesis. This compound serves as a critical intermediate for the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where its unique thiophene scaffold is highly valued. It is essential for researchers and manufacturers engaged in the synthesis of active pharmaceutical ingredients (APIs), specialty chemicals, and novel materials requiring precise molecular architecture.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and other therapeutic small molecules.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and insecticides, leveraging its bioactive thiophene core.
• Material Science Research: Serves as a building block for creating functionalized polymers, organic semiconductors, and advanced electronic materials due to its conjugated system.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new organic reactions, catalytic processes, and as a standard for analytical method development.
• Fine Chemical Production: Integral to the multi-step synthesis of complex fine chemicals and specialty additives where specific substitution patterns are required.

Basic Information

Product Name	Methyl 4-Chloro-3-Hydroxy-5-Methoxythiophene-2-Carboxylate
CAS No.	95201-98-2
Molecular Formula	C7H7ClO4S
Molecular Weight	222.65 g/mol
Synonyms	Methyl 4-chloro-3-hydroxy-5-methoxy-2-thiophenecarboxylate; 4-Chloro-3-hydroxy-5-methoxythiophene-2-carboxylic acid methyl ester; 2-Thiophenecarboxylic acid, 4-chloro-3-hydroxy-5-methoxy-, methyl ester; Methyl 4-chloro-3-hydroxy-5-methoxy-thiophene-2-carboxylate; 95201-98-2
EINECS	Contact for details

Quality Control

Our Methyl 4-Chloro-3-Hydroxy-5-Methoxythiophene-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all critical quality parameters. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light sources to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.