Description

Methyl 4-Bromo-3-Hydroxythiophene-2-Carboxylate is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. This compound matters because it serves as a critical precursor for the development of novel pharmaceuticals, agrochemicals, and functional materials, enabling the construction of complex thiophene-based molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for lead optimization and scale-up activities.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting various therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the brominated hydroxythiophene core.
• Material Science Precursor: Serves as a building block for conjugated polymers and organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Stille) and further functionalization to create diverse thiophene derivatives for research.
• Ligand and Catalyst Development: Useful for constructing complex ligands in coordination chemistry and catalysis.

Basic Information

Item	Detail
Product Name	Methyl 4-Bromo-3-Hydroxythiophene-2-Carboxylate
CAS No.	95201-93-7
Molecular Formula	C6H5BrO3S
Molecular Weight	237.07 g/mol
Synonyms	Methyl 4-bromo-3-hydroxythiophene-2-carboxylate; 4-Bromo-3-hydroxy-2-thiophenecarboxylic acid methyl ester; 2-Thiophenecarboxylic acid, 4-bromo-3-hydroxy-, methyl ester; Methyl 4-bromo-3-hydroxy-2-thiophenecarboxylate; 95201-93-7; Methyl 4-bromo-3-hydroxythiophene-2-carboxylic acid ester
EINECS	Contact for details

Quality Control

Our Methyl 4-Bromo-3-Hydroxythiophene-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed specifications are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials. This product is light-sensitive and should be stored away from light as indicated.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.