Description

4-Formyl-Bicyclo[2.2.2]octane-1-carboxylic Acid Methyl Ester is a specialized bicyclic organic compound featuring both formyl and ester functional groups on a rigid, cage-like hydrocarbon framework. This unique structure makes it a valuable and versatile advanced pharmaceutical intermediate and key building block for complex organic synthesis. It is primarily sought by R&D chemists and process development teams in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates with complex, three-dimensional structures.
• Agrochemical Synthesis: Used as a building block for developing new pesticides and herbicides with enhanced stability and specificity.
• Ligand and Catalyst Development: Employed in the creation of novel chiral ligands and organocatalysts due to its rigid, pre-organized scaffold.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialty polymers and advanced organic frameworks.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry, including new cycloaddition and functionalization reactions.
• Flavor & Fragrance Chemistry: Potential intermediate for synthesizing unique musk-like or woody aroma chemicals.

Basic Information

Product Name	4-Formyl-Bicyclo[2.2.2]octane-1-carboxylic Acid Methyl Ester
CAS No.	94994-25-9
Molecular Formula	C12H16O3
Molecular Weight	208.25 g/mol
Synonyms	Methyl 4-formylbicyclo[2.2.2]octane-1-carboxylate; 1-(Methoxycarbonyl)bicyclo[2.2.2]octane-4-carboxaldehyde; Bicyclo[2.2.2]octane-1-carboxylic acid, 4-formyl-, methyl ester; 4-Formylbicyclo[2.2.2]octane-1-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

We maintain a strict quality management system to ensure batch-to-batch consistency and high purity for our advanced intermediates. Our standard offering for 4-Formyl-Bicyclo[2.2.2]octane-1-carboxylic Acid Methyl Ester typically meets a purity specification of ≥97% (by HPLC), suitable for research and process development. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. Custom synthesis to higher purity grades (e.g., >98%, >99%) is available upon request to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage or when opening a new container. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.