Description

22,23-Dihydroavermectin B1(A) is a semi-synthetic derivative of the naturally occurring macrocyclic lactone, avermectin. This compound is valued for its potent anthelmintic and insecticidal properties, offering a crucial tool for managing parasitic infestations. It is primarily utilized by manufacturers in the veterinary pharmaceutical and agrochemical industries for the formulation of endectocide products.

Application

• Veterinary Parasiticides: A key active ingredient in injectable, pour-on, and oral formulations for livestock (cattle, sheep, swine) to control internal and external parasites.
• Agrochemicals: Used in the synthesis of advanced crop protection agents targeting mites and other agricultural pests.
• Active Pharmaceutical Ingredient (API): Serves as a critical intermediate or final API in the production of high-purity veterinary medicines.
• Research & Development: Employed in biochemical and pharmacological studies to investigate mechanisms of action against parasitic nematodes and arthropods.
• Formulation Development: Used by companies developing new delivery systems or combination products for enhanced efficacy and animal safety.

Basic Information

Product Name	22,23-Dihydroavermectin B1(A)
CAS No.	94837-49-7
Molecular Formula	C48H74O14
Molecular Weight	875.1 g/mol
Synonyms	Ivermectin B1a; 22,23-Dihydroavermectin B1a; Avermectin B1a, 22,23-dihydro-; MK-0933; 5-O-Demethyl-22,23-dihydroavermectin A1a; (10E,14E,16E,22Z)-(1R,4S,5'S,6R,6'R,8R,12S,13S,20R,21R,24S)-6'-[(S)-sec-butyl]-21,24-dihydroxy-5',11,13,22-tetramethyl-2-oxo-3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6-spiro-2'-(5',6'-dihydro-2'H-pyran)-12-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)-3-O-methyl-α-L-arabino-hexopyranoside
EINECS	Contact for details

Quality Control

Our 22,23-Dihydroavermectin B1(A) is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity. Quality is verified through comprehensive analytical testing including HPLC for assay and impurity profiling. A Certificate of Analysis (COA) detailing purity, identity, and specific tests is provided with each shipment to support your regulatory and formulation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.