Description

Amprolium Hydrochloride is a thiamine analog and a coccidiostat widely used in veterinary medicine. This compound is valued for its efficacy in preventing and treating coccidiosis, a significant parasitic disease affecting poultry and livestock. It is an essential active pharmaceutical ingredient (API) for formulators in the animal health and feed additive industries, ensuring the health and productivity of farm animals.

Application

• Veterinary Pharmaceuticals: Primary active ingredient in coccidiostat premixes, feed additives, and medicated drinking water for poultry (broilers, layers, turkeys).
• Livestock Health: Used in treatments for calves, lambs, and goats to control intestinal coccidiosis.
• Feed Manufacturing: Incorporated into complete feed formulations to provide prophylactic protection against Eimeria species infections.
• Aquaculture: Potential application in fish farming for controlling related parasitic infections, subject to regional regulatory approvals.
• Pharmaceutical Intermediates: Serves as a key chemical intermediate in the synthesis of more complex veterinary medicinal products.
• Research & Development: Used in biochemical and pharmacological studies related to thiamine metabolism and antiparasitic mechanisms.

Basic Information

Product Name	Amprolium Hydrochloride
CAS No.	137-88-2
Molecular Formula	C14H19ClN4•HCl
Molecular Weight	315.24 g/mol
Synonyms	1-[(4-Amino-2-propyl-5-pyrimidinyl)methyl]-2-methylpyridinium chloride hydrochloride; Amprol; Amprolium HCl; Amprolium Chloride Hydrochloride; Corid; Coxistac; Coxynil; Pyrimidinium, 1-[(4-amino-2-propyl-5-pyrimidinyl)methyl]-2-methyl-, chloride, hydrochloride
EINECS	205-313-5

Quality Control

Our Amprolium Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for veterinary pharmaceutical applications. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request to support your regulatory and formulation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and flow properties.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water (Karl Fischer)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.