Description

Sulfadimethoxypyrimidine is a key pharmaceutical intermediate belonging to the sulfonamide class of compounds. Its primary commercial value lies in its role as a critical building block for the synthesis of advanced sulfa drugs and other active pharmaceutical ingredients (APIs). This high-purity intermediate is essential for manufacturers in the pharmaceutical and fine chemical industries requiring consistent quality for complex synthesis processes. Global demand is driven by its application in producing medications for bacterial infections and other therapeutic areas.

Application

• Pharmaceutical Intermediate: Primary use as a core synthon for manufacturing sulfonamide-based antibiotics and other therapeutic agents.
• Veterinary Medicine Production: Utilized in the synthesis of sulfadimethoxine and related long-acting veterinary sulfonamide drugs.
• Antibacterial API Synthesis: Serves as a precursor in the production of active pharmaceutical ingredients targeting gram-positive and gram-negative bacteria.
• Research & Development: Used in medicinal chemistry research for developing new sulfonamide derivatives with modified pharmacological profiles.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for creating complex molecules in contract manufacturing.

Basic Information

Product Name	Sulfadimethoxypyrimidine
CAS No.	155-91-9
Molecular Formula	C12H14N4O4S
Molecular Weight	310.33 g/mol
Synonyms	2,4-Dimethoxy-6-sulfanilamido-1,3-diazine; Sulfadimethoxine Intermediate; 4-Amino-N-(2,6-dimethoxy-4-pyrimidinyl)benzenesulfonamide; Sulfadimethoxypyrimidine; SDM Intermediate; Sulfadimethoxin; Sulfadimethoxine Pyrimidine Base; N1-(2,6-Dimethoxy-4-pyrimidinyl)sulfanilamide
EINECS	205-851-2

Quality Control

Our Sulfadimethoxypyrimidine is manufactured under strict quality management systems to ensure batch-to-batch consistency for pharmaceutical applications. Quality is verified through comprehensive analytical testing including HPLC for purity, residual solvent analysis, and identification by spectroscopic methods. A Certificate of Analysis (COA) documenting all critical parameters is provided with each shipment. Our quality systems support compliance with cGMP, ICH Q7 guidelines, and major pharmacopoeial standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize moisture absorption. Store away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.