Description

5-Fluoro-2,3-Dihydro-(1H)-Indole is a versatile fluorinated indoline derivative, a crucial building block in advanced organic synthesis. Its value lies in its fused bicyclic structure, which serves as a privileged scaffold for constructing complex molecules with targeted biological activity. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, especially in central nervous system (CNS) and oncology therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the fluorine atom enhances bioactivity and environmental stability.
• Material Science Research: Serves as a precursor for functionalized organic materials and liquid crystals.
• Chemical Biology Probes: Employed in the design of fluorinated probes and ligands for studying enzyme mechanisms and receptor binding.
• Academic & R&D: A fundamental reagent for methodological studies in organic chemistry, including novel fluorination and cyclization reactions.

Basic Information

Product Name	5-Fluoro-2,3-Dihydro-(1H)-Indole
CAS No.	94805-51-3
Molecular Formula	C8H8FN
Molecular Weight	137.15 g/mol
Synonyms	5-Fluoroindoline; 5-Fluoro-2,3-dihydro-1H-indole; 1H-Indole, 5-fluoro-2,3-dihydro-; 5-Fluoro-2,3-dihydroindole; 5-Fluorodihydroindole; 5-Fluoroindolin; 94805-51-3; 5-Fluoro-1H-indoline
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2,3-Dihydro-(1H)-Indole is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data to support your R&D and production needs. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.