Description

3-Hydroxysenkyunolide A is a bioactive phthalide derivative, a key marker compound and active constituent found in traditional medicinal herbs such as *Ligusticum chuanxiong* Hort. Its significance lies in its potent pharmacological profile, which makes it a valuable reference standard and a promising candidate for advanced research and development. This compound is essential for pharmaceutical R&D laboratories, nutraceutical manufacturers, and academic institutions focused on cardiovascular health, neuroprotection, and anti-inflammatory therapeutics.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis (HPLC, LC-MS) of herbal extracts and finished products containing *Ligusticum chuanxiong*.
• Bioactivity and Mechanism Studies: Serves as a key investigational compound in preclinical research for its vasodilatory, antiplatelet, neuroprotective, and anti-inflammatory effects.
• Nutraceutical and Functional Food Development: Employed as a marker for standardization and quality control in dietary supplements targeting circulatory and cognitive health.
• Natural Product Chemistry Research: Used in isolation, synthesis, and structural modification studies to explore novel derivatives with enhanced bioactivity.
• Traditional Medicine Modernization: Acts as a scientific benchmark to validate the efficacy and ensure batch-to-batch consistency of traditional herbal formulations.

Basic Information

Product Name	3-Hydroxysenkyunolide A
CAS No.	94530-85-5
Molecular Formula	C12H14O4
Molecular Weight	222.24 g/mol
Synonyms	3-Hydroxysenkyunolide A; Senkyunolide H; (3Z)-3-[(1S)-4-Hydroxy-1,5-dimethyl-3-oxo-1-hexenyl]-4,5-dihydro-5-methyl-2(3H)-furanone; 3-Hydroxy-senkyunolide A; Ligusticum lactone H; Z-3-Hydroxysenkyunolide A
EINECS	Contact for details

Quality Control

We supply 3-Hydroxysenkyunolide A in high-purity grades suitable for analytical and research applications. Every batch is subjected to rigorous identity, purity, and impurity profile testing using advanced chromatographic (HPLC, TLC) and spectroscopic (MS, NMR) techniques. A comprehensive Certificate of Analysis (COA) detailing all test results is provided to ensure full traceability and compliance with your research or quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere or with desiccant to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.