Description

(E)-4-(4,8-Dimethoxy-9H-Pyrido[3,4-B]Indol-1-Yl)-4-Oxo-2-Butenoic Acid Methyl Ester is a high-purity, synthetic heterocyclic compound belonging to the β-carboline alkaloid family. This advanced pharmaceutical intermediate is valued for its complex molecular architecture, which serves as a critical building block in medicinal chemistry research and development. It is primarily sought after by R&D teams in the pharmaceutical and biotechnology sectors for the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Tool Compound: Serves as a reference standard or probe in enzymatic and receptor-binding assays to study biological pathways.
• Academic Research: Utilized in university and institutional labs for the study of β-carboline chemistry and its pharmacological properties.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for client projects.

Basic Information

Product Name	(E)-4-(4,8-Dimethoxy-9H-Pyrido[3,4-B]Indol-1-Yl)-4-Oxo-2-Butenoic Acid Methyl Ester
CAS No.	94530-77-5
Molecular Formula	C20H18N2O6
Molecular Weight	382.37 g/mol
Synonyms	Methyl (2E)-4-(4,8-dimethoxy-9H-pyrido[3,4-b]indol-1-yl)-4-oxobut-2-enoate; 4-(4,8-Dimethoxy-9H-β-carbolin-1-yl)-4-oxo-2-butenoic Acid Methyl Ester; (E)-Methyl 4-(4,8-dimethoxy-9H-pyrido[3,4-b]indol-1-yl)-4-oxobut-2-enoate; 1-(3-Methoxycarbonyl-1-oxo-2-propenyl)-4,8-dimethoxy-9H-pyrido[3,4-b]indole; β-Carboline Derivative CAS 94530-77-5
EINECS	Contact for details

Quality Control

Every batch of (E)-4-(4,8-Dimethoxy-9H-Pyrido[3,4-B]Indol-1-Yl)-4-Oxo-2-Butenoic Acid Methyl Ester is manufactured and analyzed under strict quality management protocols. Our products undergo rigorous quality testing, including HPLC, NMR, and MS, to ensure compliance with research-grade standards and customer specifications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.