Description

10,11-Dihydro-N,5-Dimethyl-5H-Dibenz[B,F]Azepin-10-Amine Oxalate is a high-purity pharmaceutical intermediate and organic building block of significant commercial interest. This compound is valued for its role as a key precursor in the synthesis of complex active pharmaceutical ingredients (APIs) and for advanced research in medicinal chemistry. It is primarily sought by manufacturers and R&D facilities in the pharmaceutical, agrochemical, and fine chemical sectors for developing new therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of tricyclic antidepressant and antipsychotic drug candidates.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in multi-step synthetic routes to build complex molecular architectures for central nervous system (CNS) targeted therapies.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the discovery of new bioactive molecules.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling.
• Fine Chemical Synthesis: Utilized in the production of specialty chemicals, dyes, and advanced materials requiring a dibenzazepine core structure.
• Agrochemical Research: Investigated as an intermediate for developing novel crop protection agents with specific biological activity.

Basic Information

Product Name	10,11-Dihydro-N,5-Dimethyl-5H-Dibenz[B,F]Azepin-10-Amine Oxalate
CAS No.	94291-64-2
Molecular Formula	C18H20N2 • C2H2O4
Molecular Weight	352.40 g/mol
Synonyms	10,11-Dihydro-N,5-dimethyl-5H-dibenz[b,f]azepin-10-amine oxalate; Desipramine Oxalate; Desmethylimipramine Oxalate; Norimipramine Oxalate; 5H-Dibenz[b,f]azepin-10-amine, 10,11-dihydro-N,5-dimethyl-, oxalate (1:1); G-35020 Oxalate; Pertofrane Impurity Oxalate
EINECS	Contact for details

Quality Control

Our 10,11-Dihydro-N,5-Dimethyl-5H-Dibenz[B,F]Azepin-10-Amine Oxalate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing purity, related substances, and residual solvents is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a dry environment to prevent product degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.