Description

p-(1-Phenylethyl)Phenyl Dihydrogen Phosphate is a specialized organophosphorus compound with a chiral center, making it a valuable intermediate in asymmetric synthesis. Its primary commercial value lies in its role as a key building block for advanced materials and active pharmaceutical ingredients (APIs). This chemical is essential for manufacturers and R&D laboratories in the pharmaceutical, agrochemical, and specialty polymer industries seeking to develop products with specific stereochemical configurations.

Application

• Pharmaceutical Intermediate: A crucial chiral building block for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug development.
• Agrochemical Synthesis: Used in the production of advanced, stereoselective pesticides and herbicides where specific chirality enhances efficacy and reduces environmental impact.
• Ligand & Catalyst Precursor: Serves as a precursor for chiral phosphine ligands and organocatalysts used in asymmetric hydrogenation and cross-coupling reactions.
• Specialty Polymer Additive: Acts as a flame retardant synergist or a chiral monomer for creating polymers with unique optical or mechanical properties.
• Analytical Chemistry: Employed as a derivatization agent or a standard in chromatographic methods for separating and analyzing chiral compounds.
• Material Science Research: Investigated for use in liquid crystals, nonlinear optical materials, and other advanced functional materials due to its molecular structure.

Basic Information

Product Name	p-(1-Phenylethyl)Phenyl Dihydrogen Phosphate
CAS No.	94200-32-5
Molecular Formula	C14H15O4P
Molecular Weight	278.24 g/mol
Synonyms	1-Phenylethylphenyl phosphate; (1-Phenylethyl)phenyl dihydrogen phosphate; 4-[(1S)-1-Phenylethyl]phenyl dihydrogen phosphate (enantiomer); p-(α-Methylbenzyl)phenyl phosphate; Phosphoric acid, [1-(4-hydroxyphenyl)ethyl]phenyl ester; Phosphoric acid mono-[4-(1-phenylethyl)phenyl] ester; (R/S)-p-(1-Phenylethyl)phenyl dihydrogen phosphate
EINECS	Contact for details

Quality Control

Our p-(1-Phenylethyl)Phenyl Dihydrogen Phosphate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis, to ensure it meets the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data (HPLC/GC) for assay, enantiomeric excess (ee), and impurity profiles are provided to guarantee supply reliability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect purity and stability. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% (for specific enantiomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.