Description

2S-(2Alpha,3Alpha,Beta,7Alpha,β-Octahydro-1H-Indole-2-Carboxylic Acid Phenyl Methyl Ester is a high-purity, advanced pharmaceutical intermediate of significant synthetic importance. This compound matters for its role as a critical chiral building block in the synthesis of complex, biologically active molecules, enabling precise stereochemical control. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly in the areas of neurology and metabolic diseases.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates.
• Asymmetric Synthesis: Utilized in stereoselective reactions to construct complex molecular architectures with high enantiomeric purity.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Used in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-fidelity intermediates.

Basic Information

Product Name	2S-(2Alpha,3Alpha,Beta,7Alpha,β-Octahydro-1H-Indole-2-Carboxylic Acid Phenyl Methyl Ester
CAS No.	94062-52-9
Molecular Formula	C16H21NO2
Molecular Weight	259.35 g/mol
Synonyms	(2S,3S,7S)-Octahydro-1H-indole-2-carboxylic acid phenylmethyl ester; (2S,3S,7S)-2-Carbobenzyloxyhexahydro-1H-indole; Benzyl (2S,3S,7S)-octahydro-1H-indole-2-carboxylate; 2S-(2α,3α,β,7α,β-Octahydro-1H-indol-2-yl)carboxylic Acid Benzyl Ester; Cbz-Protected Octahydroindole-2-carboxylic Acid Benzyl Ester; (2S,3S,7S)-1,2,3,4,5,6,7,8-Octahydroindole-2-carboxylic acid benzyl ester; BnOOC-(2S,3S,7S)-Octahydroindole
EINECS	Contact for details

Quality Control

Our 2S-(2Alpha,3Alpha,Beta,7Alpha,β-Octahydro-1H-Indole-2-Carboxylic Acid Phenyl Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity suitable for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.