Description

2,2,2-Trifluoro-n-(4-Mercaptophenyl)Acetamide is a specialized fluorinated acetamide derivative featuring a reactive mercapto group, making it a valuable building block in advanced organic synthesis. This compound is significant for its role in the development of pharmaceuticals, agrochemicals, and functional materials, where its unique trifluoromethyl and thiol functionalities enable precise molecular modifications. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for creating novel active ingredients and high-performance polymers.

Application

• Pharmaceutical Intermediate: Serves as a key synthon for the development of active pharmaceutical ingredients (APIs), particularly in antiviral and anticancer drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of novel pesticides and herbicides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science: Acts as a monomer or cross-linking agent in the synthesis of specialty polymers and resins with tailored surface properties and durability.
• Chemical Biology & Proteomics: Utilized as a reactive handle for bioconjugation, protein labeling, and the development of biochemical probes due to its thiol-reactive moiety.
• Liquid Crystal & OLED Materials: Incorporated into the molecular structure of advanced electronic display materials to modify electronic properties and stability.
• Catalyst Ligand Precursor: Employed in the synthesis of complex ligand systems for transition metal catalysis in fine chemical manufacturing.

Basic Information

Product Name	2,2,2-Trifluoro-n-(4-Mercaptophenyl)Acetamide
CAS No.	94006-35-6
Molecular Formula	C8H6F3NOS
Molecular Weight	221.20 g/mol
Synonyms	N-(4-Mercaptophenyl)-2,2,2-trifluoroacetamide; 4-Acetamidobenzenethiol, 2,2,2-trifluoro-; 2,2,2-Trifluoroacetamide, N-(4-mercaptophenyl)-; 4-(2,2,2-Trifluoroacetamido)benzenethiol; 4-(Trifluoroacetamido)thiophenol; TFAPA-SH; p-Mercaptophenyltrifluoroacetamide
EINECS	Contact for details

Quality Control

Our 2,2,2-Trifluoro-n-(4-Mercaptophenyl)Acetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to the light-sensitive and potentially oxidizable nature of the mercapto group, it is recommended to handle under an inert atmosphere for long-term storage and to minimize repeated exposure to air.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.