Description

(S)-1,2,3,4,5,6,7,8-Octahydro-1-(4-Methoxybenzyl)-2-Methylisoquinolinium Dihydrogen [R-(R*,R*)]-Tartrate is a high-purity, chiral isoquinolinium salt derivative, serving as a critical advanced pharmaceutical intermediate. Its primary value lies in its stereochemical purity, which is essential for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs) targeting specific biological pathways. This compound is particularly relevant for research and development chemists and process scale-up teams in the pharmaceutical and fine chemical industries.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of novel therapeutic agents, particularly in central nervous system (CNS) and cardiovascular drug discovery.
• Asymmetric Synthesis: Used as a precursor or catalyst in stereoselective chemical reactions to construct complex molecular architectures.
• Medicinal Chemistry Research: Serves as a scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities.
• Process Chemistry Development: Employed in the optimization and scale-up of synthetic routes for API manufacturing under GMP conditions.
• Reference Standard: Utilized as a high-purity analytical standard for method development and quality control in pharmaceutical analysis.

Basic Information

Product Name	(S)-1,2,3,4,5,6,7,8-Octahydro-1-(4-Methoxybenzyl)-2-Methylisoquinolinium Dihydrogen [R-(R*,R*)]-Tartrate
CAS No.	94006-06-1
Molecular Formula	C22H33NO7
Molecular Weight	423.50 g/mol
Synonyms	(S)-1,2,3,4,5,6,7,8-Octahydro-1-(4-methoxybenzyl)-2-methylisoquinolinium (R,R)-tartrate; (S)-1-(4-Methoxybenzyl)-2-methyl-1,2,3,4,5,6,7,8-octahydroisoquinolinium hydrogen (2R,3R)-tartrate; 1,2,3,4,5,6,7,8-Octahydro-1-(4-methoxybenzyl)-2-methylisoquinolinium (R,R)-tartrate; (S)-1,2,3,4,5,6,7,8-Octahydro-1-(4-methoxybenzyl)-2-methylisoquinolinium (R,R)-tartrate salt; (S)-1-(p-Methoxybenzyl)-2-methyl-1,2,3,4,5,6,7,8-octahydroisoquinolinium L-(+)-tartrate
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality protocols suitable for pharmaceutical development. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure high chemical and stereochemical integrity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles. We support development with custom synthesis and scale-up services under quality agreements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.