Description

Ethyl 3-(5-Bromo-1H-Indol-3-Yl)-2-Cyanoacrylate is a specialized, high-purity organic building block featuring a reactive cyanoacrylate moiety attached to a brominated indole scaffold. This compound matters as a versatile and critical intermediate for synthesizing complex molecules in advanced pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists working in medicinal chemistry, particularly for the development of novel therapeutic agents and bioactive compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in oncology and CNS research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its reactive sites for further functionalization.
• Agrochemical Synthesis: Intermediate in the development of new pesticides and herbicides with specific biological activity.
• Chemical Biology Probes: Serves as a precursor for creating fluorescent dyes or affinity probes targeting biological systems.
• Material Science Research: Potential monomer or cross-linker in the development of specialty polymers with unique optical or electronic properties.

Basic Information

Product Name	Ethyl 3-(5-Bromo-1H-Indol-3-Yl)-2-Cyanoacrylate
CAS No.	93982-61-7
Molecular Formula	C₁₄H₁₁BrN₂O₂
Molecular Weight	319.16 g/mol
Synonyms	Ethyl (5-Bromo-1H-indol-3-yl)-2-cyanoacrylate; 2-Propenoic acid, 2-cyano-3-(5-bromo-1H-indol-3-yl)-, ethyl ester; 3-(5-Bromo-1H-indol-3-yl)-2-cyanoacrylic acid ethyl ester; Ethyl 3-(5-bromoindol-3-yl)-2-cyanoacrylate; 5-Bromo-3-(2-cyano-2-ethoxycarbonylvinyl)indole; (E)-Ethyl 3-(5-bromo-1H-indol-3-yl)-2-cyanoacrylate
EINECS	Contact for details

Quality Control

Our Ethyl 3-(5-Bromo-1H-Indol-3-Yl)-2-Cyanoacrylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.