Description

1H-Indole-2-Carboxylicacid,2,3,3A,4,5,7A-Hexahydro-,Methylester,(2-α-,3A-Bta-,7A-Bta-)-(9Ci) is a high-purity, advanced pharmaceutical intermediate belonging to the hexahydroindole class of compounds. This molecule is valued for its complex stereochemistry and functional groups, making it a critical building block in modern synthetic organic chemistry. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and other therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic compounds.
• Asymmetric Synthesis: Serves as a sophisticated starting material or intermediate for constructing molecules with specific stereochemical configurations.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for methodological development in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	1H-Indole-2-Carboxylicacid,2,3,3A,4,5,7A-Hexahydro-,Methylester,(2-α-,3A-Bta-,7A-Bta-)-(9Ci)
CAS No.	93967-83-0
Molecular Formula	C11H17NO2
Molecular Weight	195.26 g/mol
Synonyms	Methyl (2α,3aβ,7aβ)-2,3,3a,4,5,7a-hexahydro-1H-indole-2-carboxylate; Hexahydro-1H-indole-2-carboxylic acid methyl ester; (2α,3aβ,7aβ)-Methyl octahydro-1H-indole-2-carboxylate; 93967-83-0; Methyl 2,3,3a,4,5,7a-hexahydro-1H-indole-2-carboxylate; (2S,3aS,7aS)-Methyl 2,3,3a,4,5,7a-hexahydro-1H-indole-2-carboxylate (stereoisomer); Indole-2-carboxylic acid, 2,3,3a,4,5,7a-hexahydro-, methyl ester, (2α,3aβ,7aβ)-
EINECS	Contact for details

Quality Control

Our high-purity pharmaceutical intermediate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral assay, to ensure it meets the stringent requirements for research and development use. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.