Description

Diethyl [(5-Bromo-1H-Indol-3-Yl)Methylene]Malonate is a high-purity brominated indole derivative, a crucial synthetic intermediate in advanced organic chemistry. This compound is valued for its versatile reactivity, particularly in the construction of complex heterocyclic frameworks and as a key building block for active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel compounds and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a building block for creating advanced organic materials, such as organic semiconductors and light-emitting diodes (OLEDs).
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological processes and enzyme functions.
• Academic & Industrial R&D: Essential for methodological development in organic synthesis and for creating libraries of novel chemical entities.

Basic Information

Product Name	Diethyl [(5-Bromo-1H-Indol-3-Yl)Methylene]Malonate
CAS No.	93941-03-8
Molecular Formula	C₁₆H₁₆BrNO₄
Molecular Weight	366.21 g/mol
Synonyms	Diethyl (5-Bromo-1H-indol-3-ylmethylene)malonate; Diethyl 2-[(5-Bromo-1H-indol-3-yl)methylene]malonate; 5-Bromo-3-[(ethoxycarbonyl)methylidene]-1H-indole-2-carboxylic acid ethyl ester; (5-Bromo-1H-indol-3-ylmethylene)malonic acid diethyl ester; Ethyl (5-bromo-1H-indol-3-yl)methylene malonate; 93941-03-8; 5-Bromo-3-carbethoxyethylidene indole-2-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Diethyl [(5-Bromo-1H-Indol-3-Yl)Methylene]Malonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. The container should be kept tightly sealed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.