Description

[1R,2R,4R,(+)]-4α-(1-Hydroxy-1-Methylethyl)-1-Methyl-1β,2α-Cyclohexanediol is a high-purity, stereochemically defined chiral diol compound. This material is valued as a critical chiral building block and intermediate in advanced organic synthesis, where precise stereochemistry is paramount. It is primarily sought after by research and development teams in the pharmaceutical and fine chemical industries for the synthesis of complex, biologically active molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in stereoselective synthesis.
• Asymmetric Catalyst Ligand Precursor: Used in the development and preparation of chiral ligands for asymmetric catalysis, enabling the production of enantiomerically pure compounds.
• Fine Chemical Synthesis: Serves as a versatile building block for creating complex natural products, flavors, fragrances, and other specialty chemicals requiring specific stereochemistry.
• Academic & Industrial Research: A valuable reference standard and starting material in methodological development for organic and medicinal chemistry research programs.
• Agrochemical Intermediate: Potential use in the synthesis of chiral agrochemicals where specific enantiomers exhibit desired biological activity.

Basic Information

Product Name	[1R,2R,4R,(+)]-4α-(1-Hydroxy-1-Methylethyl)-1-Methyl-1β,2α-Cyclohexanediol
CAS No.	93861-31-5
Molecular Formula	C10H20O3
Molecular Weight	188.26 g/mol
Synonyms	(+)-(1R,2R,4R)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexane-1,2-diol; (1R,2R,4R)-p-Menthane-1,2,8-triol; (1R,2R,4R)-4-(1-Hydroxy-1-methylethyl)-1-methylcyclohexane-1,2-diol; (1R,2R,4R)-4-(2-Hydroxy-2-propyl)-1-methyl-1,2-cyclohexanediol; L-Menthane-1,2,8-triol; Chiral Cyclohexanediol Derivative; Stereoisomeric Diol Building Block
EINECS	Contact for details

Quality Control

Our [1R,2R,4R,(+)]-4α-(1-Hydroxy-1-Methylethyl)-1-Methyl-1β,2α-Cyclohexanediol is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure high enantiomeric excess (ee) and chemical purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption. Recommended long-term storage at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.