Description

4-[(1S)-1-Hydroxyethyl]Phenol is a chiral phenolic compound of significant interest in advanced organic synthesis. Its value lies in its role as a key chiral building block and intermediate for the production of enantiomerically pure pharmaceuticals and fine chemicals. This product is essential for research and development chemists and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce stereochemical complexity into their target molecules.

Application

• Pharmaceutical Intermediate: A critical chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting neurological and cardiovascular systems.
• Asymmetric Synthesis: Used as a starting material or auxiliary in catalytic asymmetric reactions to construct complex molecular architectures with high enantiomeric purity.
• Ligand and Catalyst Development: Serves as a scaffold for developing novel chiral ligands and organocatalysts used in enantioselective transformations.
• Fine Chemical Production: Employed in the manufacture of high-value specialty chemicals, including flavors, fragrances, and advanced materials where optical purity is paramount.
• Agrochemical Research: Investigated as an intermediate for developing new chiral pesticides and herbicides with improved efficacy and environmental profiles.
• Academic & Industrial R&D: A valuable compound for methodological research in organic chemistry and process development in pilot-scale facilities.

Basic Information

Product Name	4-[(1S)-1-Hydroxyethyl]Phenol
CAS No.	93781-59-0
Molecular Formula	C8H10O2
Molecular Weight	138.16 g/mol
Synonyms	(S)-1-(4-Hydroxyphenyl)ethanol; (S)-4-(1-Hydroxyethyl)phenol; (S)-p-Hydroxyphenethyl alcohol; (1S)-1-(4-Hydroxyphenyl)ethan-1-ol; (S)-HPE; L-4-Hydroxyphenylethanol; (S)-(-)-1-(4-Hydroxyphenyl)ethanol
EINECS	Contact for details

Quality Control

Our 4-[(1S)-1-Hydroxyethyl]Phenol is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and enantiomeric excess meet stringent specifications. Certificates of Analysis (COA) detailing chiral purity (typically by chiral HPLC), assay, and impurity profiles are provided and available upon request, supporting compliance in cGMP and ISO environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.