Description

Tetrahydro-2-[(2R)-1,1,2-Trimethyl-3-(Phenylsulfonyl)Propoxy]-2H-Pyran-D6 is a deuterated organic compound of significant interest in advanced chemical synthesis and analytical research. This material matters for its role as a stable isotope-labeled intermediate, enabling precise metabolic and pharmacokinetic studies. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers developing novel therapeutic agents and conducting sophisticated analytical method development.

Application

• As a deuterated internal standard in quantitative mass spectrometry (LC-MS/MS, GC-MS) for bioanalytical method development.
• As a key synthetic intermediate in the research and development of novel pharmaceutical compounds.
• For use in metabolic pathway tracing and drug metabolism studies (DMPK) within preclinical research.
• In the synthesis of isotope-labeled probes for use in nuclear magnetic resonance (NMR) spectroscopy.
• As a specialty building block for contract research organizations (CROs) and fine chemical suppliers.
• For academic research in organic chemistry, focusing on reaction mechanisms involving chiral centers and sulfonyl groups.

Basic Information

Product Name	Tetrahydro-2-[(2R)-1,1,2-Trimethyl-3-(Phenylsulfonyl)Propoxy]-2H-Pyran-D6
CAS No.	93748-47-1
Molecular Formula	C₁₉H₂₂D₆O₃S
Molecular Weight	342.52 g/mol
Synonyms	2H-Pyran, tetrahydro-2-[(1R)-1,1,2-trimethyl-3-(phenylsulfonyl)propoxy]-, hexadeuterated; Tetrahydro-2-[(1R)-1,1,2-trimethyl-3-(phenylsulfonyl)propoxy]-2H-pyran-d6; Deuterated THP ether sulfone; (R)-Isomer of deuterated phenylsulfonyl propyl THP ether; Hexadeuterated Tetrahydro-2-[(2R)-1,1,2-Trimethyl-3-(Phenylsulfonyl)Propoxy]-2H-Pyran; Chiral deuterated sulfone-THP ether; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized to confirm identity, isotopic purity (D-enrichment), and chemical purity, typically exceeding 95% by HPLC. Certificates of Analysis (COA) detailing specific batch results for assay, chiral purity, and residual solvents are available upon request. We adhere to a cGMP-compliant quality management system for traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container sealed in a dry, inert atmosphere to maintain stability and prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.