Description

Sodium 2-Keto-4-Methyl-D3-Pentanoate is a high-purity, isotopically labeled sodium salt of a branched-chain keto acid. This compound is critical for research and development requiring precise metabolic tracing and analytical accuracy. It is primarily utilized by pharmaceutical researchers, analytical chemists, and manufacturers of diagnostic reagents in advanced metabolic studies and stable isotope labeling applications.

Application

• Stable Isotope Labeling in Metabolic Research: Used as a deuterium-labeled precursor or internal standard for studying branched-chain amino acid (BCAA) metabolism, ketone body utilization, and related metabolic pathways.
• Pharmaceutical Development: Serves as a key intermediate or analytical standard in the synthesis and quality control of novel therapeutics targeting metabolic disorders.
• Mass Spectrometry & Analytical Chemistry: Employed as a high-purity internal standard for quantitative analysis via LC-MS/MS and GC-MS, ensuring accurate measurement of endogenous metabolites in complex biological matrices.
• Diagnostic Reagent Manufacturing: Incorporated into calibrators and controls for clinical diagnostic kits that measure specific metabolites related to inborn errors of metabolism.
• Nutritional & Sports Science Research: Used in tracer studies to investigate the effects of exercise and nutrition on protein and energy metabolism.

Basic Information

Product Name	Sodium 2-Keto-4-Methyl-D3-Pentanoate
CAS No.	93523-67-2
Molecular Formula	C6H6D3NaO3
Molecular Weight	155.14 g/mol
Synonyms	Sodium 4-Methyl-2-oxopentanoate-d3; Sodium α-Ketoisocaproate-d3 (KIC-d3); Sodium 2-Oxo-4-methylpentanoate-d3; Sodium Ketoleucine-d3; (4-Methyl-2-oxopentanoic-5,5,5-d3 acid) sodium salt; 2-Keto-4-methyl-D3-pentanoic acid sodium salt; Sodium 2-Ketoisocaproate-d3
EINECS	Contact for details

Quality Control

Every batch of Sodium 2-Keto-4-Methyl-D3-Pentanoate is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and isotopic enrichment meet exacting standards. Our quality system emphasizes traceability and consistency. A comprehensive Certificate of Analysis (COA) detailing purity (by HPLC/NMR), isotopic purity (D-enrichment), and specific tests is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. Once opened, the container should be flushed with an inert gas (e.g., argon or nitrogen) and resealed immediately.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.