Description

Carbamic Acid, (3-Mercaptopropyl)-, 1,1-Dimethylethyl Ester (9Ci) is a specialized organosulfur compound featuring both a protected mercaptan (thiol) group and a tert-butyl carbamate moiety. This dual functionality makes it a valuable intermediate for introducing sulfhydryl groups in a controlled manner under mild conditions, which is critical for synthesizing complex molecules with high selectivity. It is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in peptide mimetics, linker chemistry, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing thiol-protected side chains in peptide and protein-based drugs.
• Peptide Synthesis: Serves as a building block for incorporating cysteine analogs or creating disulfide bridges in synthetic peptides and peptide mimetics.
• Bioconjugation & Linker Chemistry: Acts as a key reagent for creating cleavable linkers in antibody-drug conjugates (ADCs) and other targeted therapeutic platforms.
• Agrochemical Research: Employed in the development of novel herbicides, fungicides, and insecticides where the thiol group is essential for biological activity.
• Material Science: Utilized as a functional monomer or cross-linking agent in the production of specialty polymers and resins with specific surface properties.
• Chemical Synthesis: Functions as a versatile protecting group reagent for mercaptans in multi-step organic synthesis, allowing for sequential deprotection strategies.

Basic Information

Product Name	Carbamic Acid, (3-Mercaptopropyl)-, 1,1-Dimethylethyl Ester (9Ci)
CAS No.	93472-93-6
Molecular Formula	C8H17NO2S
Molecular Weight	191.29 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-3-mercaptopropylamine; 3-[(tert-Butoxycarbonyl)amino]-1-propanethiol; N-Boc-3-mercaptopropylamine; tert-Butyl (3-mercaptopropyl)carbamate; N-(tert-Butoxycarbonyl)-3-aminopropanethiol; Boc-NH-(CH2)3-SH; t-BOC-3-mercaptopropylamine
EINECS	Contact for details

Quality Control

Our Carbamic Acid, (3-Mercaptopropyl)-, 1,1-Dimethylethyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability, consistency, and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a cool, dry, and well-ventilated place. Due to its easily oxidized nature, minimize exposure to air during handling. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.