Description

2-Chloro-4-Fluorobenzyl Chloride is a versatile and reactive halogenated benzyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both chloro and fluoro substituents, makes it an essential intermediate for introducing specific aromatic motifs into target molecules. This compound is particularly valuable for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to synthesize active ingredients and functional materials requiring precise halogenation patterns.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for molecules containing halogenated benzyl groups.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides, where the chloro-fluorobenzyl moiety can enhance biological activity and stability.
• Liquid Crystal & OLED Material Production: Serves as a starting material for synthesizing advanced functional materials used in electronic displays and lighting.
• Organic Synthesis Building Block: Employed in various coupling reactions (e.g., Suzuki, Heck) and nucleophilic substitutions to construct complex aromatic compounds.
• Dye & Pigment Manufacturing: Acts as an intermediate for creating specialized halogenated dyes and colorants.
• Polymer Modification: Used to introduce functional benzyl groups into polymer chains to alter physical or chemical properties.

Basic Information

Product Name	2-Chloro-4-Fluorobenzyl Chloride
CAS No.	93286-22-7
Molecular Formula	C7H5Cl2F
Molecular Weight	179.02 g/mol
Synonyms	1-(Chloromethyl)-2-chloro-4-fluorobenzene; α,2-Dichloro-4-fluorotoluene; 2-Chloro-4-fluoro-α-chlorotoluene; (2-Chloro-4-fluorophenyl)methyl chloride; 4-Fluoro-2-chlorobenzyl chloride; 2-Chloro-4-fluorobenzylchloride; Benzene, 1-(chloromethyl)-2-chloro-4-fluoro-
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Fluorobenzyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to exclude moisture. Keep away from strong bases and incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.