Description

1-Chloro-6-Fluorohexane is a versatile bifunctional halogenated alkane, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring terminal chloro and fluoro groups separated by a hexyl chain, makes it an invaluable intermediate for introducing fluorinated segments into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries seeking to develop novel compounds with modified physical, chemical, or biological properties.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated active pharmaceutical ingredients (APIs) and prodrugs, where fluorine substitution can enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used to create fluorinated pesticides, herbicides, and fungicides, leveraging fluorine's ability to improve lipophilicity and target binding.
• Liquid Crystal & OLED Materials: Acts as a fluorinated linker or side-chain in the production of advanced electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer Modification: Employed to introduce fluorinated units into polymers, imparting valuable properties such as oil/water repellency, chemical resistance, and low surface energy.
• Cross-coupling Reactions: Serves as an electrophile in various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Negishi) to form carbon-carbon bonds.
• Surface Active Agents: Utilized in the synthesis of fluorinated surfactants and coatings with superior performance in demanding environments.

Basic Information

Product Name	1-Chloro-6-Fluorohexane
CAS No.	1550-09-0
Molecular Formula	C6H12ClF
Molecular Weight	138.61 g/mol
Synonyms	6-Chloro-1-fluorohexane; 1-Fluoro-6-chlorohexane; Hexane, 1-chloro-6-fluoro-; 6-Fluorohexyl chloride; ω-Chloro-ω-fluorohexane; 6-Fluoro-1-chlorohexane; F(CH2)6Cl
EINECS	Contact for details

Quality Control

Our 1-Chloro-6-Fluorohexane is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment, guaranteeing it meets the exacting standards required for research and industrial synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and concentration changes. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Density (20°C)	~1.00 g/mL
Boiling Point	~155-160°C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.