Description

(+)-[(R)-1-Bromoethyl]Benzene is a high-purity chiral building block of significant value in asymmetric synthesis. Its defined stereochemistry at the benzylic position makes it a crucial electrophile for constructing complex molecules with high enantiomeric purity. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries developing active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of enantiomerically pure drugs, particularly for central nervous system (CNS) agents and cardiovascular medications.
• Asymmetric Synthesis: Serves as an electrophile in nucleophilic substitution reactions (SN2) to introduce a chiral phenethyl moiety with retention or inversion of configuration.
• Ligand and Catalyst Development: Used in the preparation of chiral ligands for transition metal catalysis and organocatalysts.
• Agrochemical Research: Building block for creating chiral herbicides, fungicides, and plant growth regulators with improved efficacy and environmental profile.
• Material Science: Monomer or precursor for synthesizing chiral polymers and liquid crystals with specific optical properties.
• Academic & R&D: Valuable reagent for methodological studies in organic chemistry and stereochemistry at universities and corporate R&D centers.

Basic Information

Product Name	(+)-[(R)-1-Bromoethyl]Benzene
CAS No.	1459-14-9
Molecular Formula	C8H9Br
Molecular Weight	185.06 g/mol
Synonyms	(R)-(+)-1-Bromoethylbenzene; (R)-(+)-α-Methylbenzyl bromide; (R)-1-Phenylethyl bromide; (R)-Styryl bromide; (+)-1-Bromo-1-phenylethane; (R)-Bromoethylbenzene; (R)-Bromo(1-phenylethyl); (R)-C6H5CH(Br)CH3
EINECS	Contact for details

Quality Control

Our (+)-[(R)-1-Bromoethyl]Benzene is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC or GC, to ensure high enantiomeric excess (e.e.) and chemical purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. Due to its light-sensitive and organic solvent nature, handle and store under an inert atmosphere (e.g., nitrogen or argon) for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC/GC)	≥ 99.0% e.e.
Specific Rotation [α]D20	+40.0° to +44.0° (c=1 in CHCl3)
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.