Description

Ethanone, 1-(Tetrahydro-4-Hydroxy-3-Thienyl)-, cis- (9Ci) is a high-purity chiral building block featuring a fused tetrahydrothiophene ring system with hydroxyl and acetyl functional groups. This compound is valued for its defined stereochemistry and functional group versatility, making it a critical intermediate in advanced organic synthesis. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and antiviral therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced, stereospecific pesticides and herbicides where the specific spatial orientation of the molecule is crucial for biological activity.
• Chemical Research: Serves as a versatile building block in academic and industrial laboratories for methodological studies in asymmetric synthesis and heterocyclic chemistry.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances that require high-purity, complex intermediates.

Basic Information

Product Name	Ethanone, 1-(Tetrahydro-4-Hydroxy-3-Thienyl)-, cis- (9Ci)
CAS No.	93198-76-6
Molecular Formula	C6H10O2S
Molecular Weight	146.21 g/mol
Synonyms	cis-1-(Tetrahydro-4-hydroxy-3-thienyl)ethanone; 1-(4-Hydroxy-3-thiolanyl)ethanone, cis-; 4-Hydroxy-3-acetyltetrahydrothiophene, cis-; (3R,4S)-4-Hydroxy-3-acetyltetrahydrothiophene; (3S,4R)-4-Hydroxy-3-acetyltetrahydrothiophene; THT-HA; Tetrahydrothiophene hydroxy ketone intermediate
EINECS	Contact for details

Quality Control

Our Ethanone, 1-(Tetrahydro-4-Hydroxy-3-Thienyl)-, cis- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) confirming identity, purity, and stereochemical integrity is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.