Description

4-Fluorobenzyl-2,3,5,6-D4 Alcohol is a deuterium-labeled analog of 4-fluorobenzyl alcohol, a valuable building block in synthetic organic chemistry. This isotopically labeled compound is essential for creating internal standards and labeled tracers used in advanced analytical techniques, ensuring precise and reliable quantitative measurements. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and analytical chemistry sectors for drug metabolism studies, pharmacokinetics, and environmental fate analysis.

Application

• Internal Standard for Mass Spectrometry (MS): Serves as a critical, non-interfering reference compound in quantitative LC-MS and GC-MS analysis for accurate measurement of its non-deuterated counterpart.
• Pharmaceutical Research & Development: Used as a labeled precursor in the synthesis of deuterated drug candidates for metabolism and pharmacokinetic (DMPK) studies.
• Metabolite Identification: Aids in the tracking and identification of drug metabolites in biological matrices during ADME (Absorption, Distribution, Metabolism, and Excretion) studies.
• Analytical Reference Standard: Provides a high-purity benchmark for method development, validation, and quality control in analytical laboratories.
• Isotope Dilution Analysis: Employed in precise quantification techniques to improve accuracy and correct for analyte loss during sample preparation.
• Chemical Synthesis Intermediate: Acts as a specialized building block for incorporating deuterium atoms into more complex molecules for research purposes.

Basic Information

Product Name	4-Fluorobenzyl-2,3,5,6-D4 Alcohol
CAS No.	93111-26-3
Molecular Formula	C7H3D4FO
Molecular Weight	128.15 g/mol
Synonyms	(2,3,5,6-D4)-4-Fluorobenzyl Alcohol; 4-Fluorobenzyl-d4 Alcohol; (4-Fluorophenyl)methan-d4-ol; α,α,2,3,5,6-D6-4-Fluorobenzyl Alcohol; Deutero-4-Fluorobenzyl Alcohol; 4-Fluoro(D4)benzyl Alcohol; Benzyl-d4 Alcohol, 4-fluoro-; 93111-26-3
EINECS	Contact for details

Quality Control

Our 4-Fluorobenzyl-2,3,5,6-D4 Alcohol is manufactured under controlled conditions to ensure high isotopic and chemical purity. Each batch undergoes rigorous analytical testing, including NMR (¹H, ¹³C, ¹⁹F), mass spectrometry, and HPLC, to confirm identity, isotopic enrichment (D atom% >98%), and chemical purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The container should be kept in a well-ventilated area. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D atom%)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.