Description

4-Fluorobenzoic-D4 Acid is a deuterated isotopologue of 4-fluorobenzoic acid, where four hydrogen atoms are replaced by deuterium, a stable isotope of hydrogen. This high-purity labeled compound is essential for applications requiring precise internal standards, minimizing spectral interference in analytical techniques. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and analytical chemistry sectors for quantitative mass spectrometry, metabolic studies, and NMR spectroscopy.

Application

• Internal Standard for Quantitative Analysis: Serves as a critical reference standard in LC-MS and GC-MS for the accurate quantification of 4-fluorobenzoic acid and related metabolites in complex biological and environmental matrices.
• Pharmaceutical Research & Development: Used in drug metabolism and pharmacokinetics (DMPK) studies to track the fate of fluorinated drug candidates and their metabolites.
• NMR Spectroscopy Solvent & Reagent: Acts as a deuterated solvent shift reagent or a non-interfering standard in nuclear magnetic resonance spectroscopy due to its isotopic purity.
• Agrochemical Analysis: Employed in the development and validation of analytical methods for detecting fluorinated pesticide residues and their degradation products.
• Chemical Synthesis Intermediate: Functions as a labeled building block for the synthesis of more complex deuterated compounds for research purposes.
• Environmental Tracing: Applied in scientific studies to monitor the environmental breakdown and movement of fluorinated aromatic compounds.

Basic Information

Product Name	4-Fluorobenzoic-D4 Acid
CAS No.	93111-25-2
Molecular Formula	C7D4FO2
Molecular Weight	144.13 g/mol
Synonyms	Benzoic-2,3,5,6-d4 acid, 4-fluoro-; 4-Fluoro-d4-benzoic Acid; Deuteronated 4-Fluorobenzoic Acid; [2,3,5,6-2H4]-4-Fluorobenzoic Acid; p-Fluorobenzoic-d4 Acid; 4-Fluorobenzoic-2,3,5,6-d4 Acid; (2,3,5,6-2H4)Benzoic acid, 4-fluoro-; Perdeuterated 4-Fluorobenzoic Acid (on the ring)
EINECS	Contact for details

Quality Control

Our 4-Fluorobenzoic-D4 Acid is manufactured under controlled conditions to ensure exceptional isotopic and chemical purity, meeting the stringent requirements of analytical and research applications. Each batch undergoes comprehensive analysis, including HPLC, NMR, and mass spectrometry, to confirm identity, chemical purity, and deuterium enrichment. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and compliance with your quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. The product is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0% (chemical purity)
Deuterium Enrichment (MS)	≥98 atom % D
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.