Description

1-(5-Carboxythiophen-2-Yl)-1H-Indole-5-Carboxylic Acid is a high-purity, bifunctional organic building block featuring both indole and thiophene carboxylic acid moieties. This compound is critical for advanced research and development in pharmaceutical chemistry, enabling the synthesis of novel, complex molecular architectures. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for creating targeted bioactive molecules and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and plant growth regulators with enhanced specificity.
• Organic Electronic Materials: Serves as a monomer or building block for conjugated polymers and small molecules used in organic light-emitting diodes (OLEDs) and organic photovoltaics (OPVs).
• Ligand Synthesis: Utilized for constructing complex chelating ligands in coordination chemistry and catalysis.
• Fluorescent Probe Development: The indole-thiophene core is valuable for creating sensitive fluorescent tags and sensors for biological imaging.
• Peptidomimetics & Bioconjugation: The carboxylic acid groups allow for coupling to peptides or other biomolecules, facilitating the creation of novel bioconjugates.

Basic Information

Product Name	1-(5-Carboxythiophen-2-Yl)-1H-Indole-5-Carboxylic Acid
CAS No.	93104-74-6
Molecular Formula	C14H9NO4S
Molecular Weight	287.29 g/mol
Synonyms	5-[5-Carboxy-1H-indol-1-yl]thiophene-2-carboxylic acid; 1-(5-Carboxy-2-thienyl)-1H-indole-5-carboxylic acid; 1H-Indole-5-carboxylic acid, 1-(5-carboxy-2-thienyl)-; 1-(2-Thienyl)-1H-indole-5,2'-dicarboxylic acid; TCI-I0426; AKOS005258155; 1-(5-Carboxythiophen-2-yl)indole-5-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-(5-Carboxythiophen-2-Yl)-1H-Indole-5-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are available for every shipment upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.