Description

Diethyl 2-[(5-Nitro-1H-Indol-3-Yl)Methyl]Propanedioate is a specialized nitroindole derivative, serving as a critical synthetic intermediate in advanced organic synthesis. Its molecular architecture, featuring both an indole core and a reactive malonate ester moiety, makes it a versatile building block for constructing complex heterocyclic systems. This compound is primarily utilized by research institutions and pharmaceutical development teams focused on creating novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel indole-based drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Research: Used in the development of new herbicides and plant growth regulators that leverage the biological activity of the nitroindole scaffold.
• Organic Synthesis Building Block: Employed in complex multi-step syntheses, including cyclization and functional group transformation reactions, due to its reactive diester group.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and functional organic materials with unique electronic properties.
• Biochemical Probe Development: Serves as a starting material for creating fluorescent tags or enzyme inhibitors used in biochemical assays and diagnostic research.

Basic Information

Product Name	Diethyl 2-[(5-Nitro-1H-Indol-3-Yl)Methyl]Propanedioate
CAS No.	93020-27-0
Molecular Formula	C₁₇H₂₀N₂O₆
Molecular Weight	348.35 g/mol
Synonyms	Diethyl (5-Nitro-1H-indol-3-ylmethyl)malonate; Propanedioic acid, 2-[(5-nitro-1H-indol-3-yl)methyl]-, diethyl ester; 2-[(5-Nitro-1H-indol-3-yl)methyl]propanedioic acid diethyl ester; Diethyl (5-nitroindol-3-ylmethyl)malonate; 3-(Diethoxycarbonylmethyl)methyl-5-nitroindole; 93020-27-0; 5-Nitro-3-malonylmethylindole diethyl ester
EINECS	Contact for details

Quality Control

Our Diethyl 2-[(5-Nitro-1H-Indol-3-Yl)Methyl]Propanedioate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.