Description

2-(Piperidin-3-Yl)-1H-Indole is a high-purity, advanced pharmaceutical intermediate featuring a unique indole-piperidine hybrid scaffold. This compound is of significant value for medicinal chemistry research and development, serving as a versatile building block for constructing novel bioactive molecules. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for the synthesis of potential drug candidates targeting central nervous system and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting neurological receptors.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Ligand Development: Employed in the design and synthesis of selective ligands for various G-protein coupled receptors (GPCRs).
• Chemical Biology Probes: Serves as a starting material for creating tool compounds to study biological pathways and protein functions.
• Process Chemistry: Used in route scouting and optimization for the scalable production of active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in university and institutional labs for fundamental organic synthesis and heterocyclic chemistry studies.

Basic Information

Product Name	2-(Piperidin-3-Yl)-1H-Indole
CAS No.	92960-62-8
Molecular Formula	C13H16N2
Molecular Weight	200.28 g/mol
Synonyms	1H-Indole, 2-(3-piperidinyl)-; 2-(3-Piperidyl)indole; 3-(1H-Indol-2-yl)piperidine; 2-(Piperidin-3-yl)-1H-indole; 2-(3-Piperidinyl)-1H-indole; 92960-62-8
EINECS	Contact for details

Quality Control

Every batch of 2-(Piperidin-3-Yl)-1H-Indole is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for each lot to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.