Description

3-Aminopropyl Methanethiosulfonate, Hydrobromide is a specialized organosulfur compound featuring a reactive thiosulfonate group and a primary amine functionality. This dual reactivity makes it a valuable intermediate for the synthesis of functionalized materials and for bioconjugation applications, particularly in the modification of proteins and surfaces. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors.

Application

• Bioconjugation Reagent: For site-specific modification of cysteine residues in proteins and peptides to introduce functional groups or labels.
• Surface Functionalization: Used to create self-assembled monolayers (SAMs) on gold or other surfaces for biosensor and diagnostic device development.
• Crosslinking Agent: In polymer chemistry and material science to create crosslinked networks with specific properties.
• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of more complex drug candidates and active pharmaceutical ingredients (APIs).
• Proteomics Research: A tool for studying protein structure, function, and interactions through chemical tagging.
• Linker Chemistry: For attaching various molecules (e.g., drugs, dyes, polymers) to nanoparticles or other carrier systems.

Basic Information

Product Name	3-Aminopropyl Methanethiosulfonate, Hydrobromide
CAS No.	92953-13-4
Molecular Formula	C4H12BrNO2S2
Molecular Weight	242.18 g/mol
Synonyms	3-(Methanethiosulfonyl)propylamine hydrobromide; (3-Aminopropyl) methanethiosulfonate hydrobromide; APMT hydrobromide; 3-Aminopropyl methanesulfonothioate hydrobromide; 1-Amino-3-(methanesulfonylthio)propane hydrobromide; MTS reagent derivative; Thiol-reactive amine linker HBr salt
EINECS	Contact for details

Quality Control

Our 3-Aminopropyl Methanethiosulfonate, Hydrobromide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and industrial applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.