Description

4-(n-Maleimido)Benzophenone is a specialized heterobifunctional crosslinking agent that combines a photoactivatable benzophenone group with a maleimide functionality. This dual reactivity makes it a critical reagent for creating stable, covalent linkages between biomolecules and surfaces under controlled conditions. It is primarily utilized by researchers and manufacturers in the life sciences, polymer chemistry, and materials science sectors for applications such as surface functionalization, bioconjugation, and the development of advanced polymeric materials.

Application

• Bioconjugation and Protein Labeling: Used to covalently attach proteins, peptides, or antibodies to various carriers, surfaces, or other biomolecules via the maleimide-thiol chemistry, followed by UV-induced crosslinking of the benzophenone group.
• Surface Immobilization and Functionalization: Enables the permanent grafting of biomolecules or polymers onto surfaces (e.g., gold, glass, polymers) for biosensor development, microarray fabrication, and creating bioactive coatings.
• Polymer Modification and Crosslinking: Serves as a key monomer or crosslinker in the synthesis of functional polymers, hydrogels, and dendrimers with tailored photochemical properties.
• Affinity Chromatography Ligand Coupling: Facilitates the stable immobilization of specific ligands onto chromatographic resins for purification processes.
• Materials Science Research: Employed in the development of novel photo-responsive materials, self-assembled monolayers (SAMs), and nanocomposites.
• Diagnostic Assay Development: Used in the fabrication of diagnostic devices where stable and oriented immobilization of capture molecules is required.

Basic Information

Product Name	4-(n-Maleimido)Benzophenone
CAS No.	92944-71-3
Molecular Formula	C18H13NO3
Molecular Weight	291.30 g/mol
Synonyms	4-Maleimidobenzophenone; N-(4-Benzoylphenyl)maleimide; 4-(Maleimidophenyl) benzophenone; 1-(4-Benzoylphenyl)-1H-pyrrole-2,5-dione; 4-Maleimidophenyl benzophenone; Benzophenone-4-maleimide; p-Maleimidobenzophenone
EINECS	Contact for details

Quality Control

Our 4-(n-Maleimido)Benzophenone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods for structural confirmation, to ensure it meets the high standards required for research and industrial applications. A Certificate of Analysis (COA) detailing purity, identity, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to moisture or light should be avoided to maintain stability and performance. Keep container tightly sealed under an inert atmosphere when not in use for extended periods.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.