Description

6-Fluoro-6-Desoxyoxymorphone is a fluorinated derivative of the potent opioid oxymorphone, representing a key intermediate in advanced pharmaceutical research and development. This compound is critical for medicinal chemists exploring structure-activity relationships (SAR) and developing novel analgesic agents with modified receptor binding profiles. It is primarily utilized by research institutions and pharmaceutical companies engaged in neuropharmacology, pain management research, and the synthesis of specialized reference standards.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel opioid receptor ligands and potential analgesic candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to investigate the impact of fluorination on potency, selectivity, and metabolic stability of opioid compounds.
• Reference Standard: Employed as an analytical standard in method development and quality control for forensic and pharmaceutical laboratories.
• Biochemical Research: Utilized in vitro studies to probe opioid receptor subtypes (e.g., μ, κ, δ) and understand signal transduction pathways.
• Metabolite Synthesis: Acts as a precursor for synthesizing potential fluorinated metabolites for pharmacological and toxicological profiling.

Basic Information

Product Name	6-Fluoro-6-Desoxyoxymorphone
CAS No.	92593-44-7
Molecular Formula	C17H18FNO4
Molecular Weight	319.33 g/mol
Synonyms	6-Fluoro-6-desoxyoxymorphone; 6-Fluorooxymorphone; 14-Hydroxy-6-fluorodihydromorphinone; 4,5α-Epoxy-6-fluoro-3,14-dihydroxy-17-methylmorphinan-6-ol; 6-Fluoro-14-hydroxydihydromorphinone; 6-Fluoro-6-deoxyoxymorphone; 6-Fluorodihydro-14-hydroxycodeinone
EINECS	Contact for details

Quality Control

Our 6-Fluoro-6-Desoxyoxymorphone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.