Description

Methyl 2-Acetamido-4,5,6,7-Tetrahydrobenzo[B]Thiophene-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its tetrahydrobenzo[b]thiophene core structure. This compound is a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), offering a versatile scaffold for medicinal chemistry research and development. It is essential for R&D and production teams in the pharmaceutical and fine chemical industries seeking reliable, high-quality intermediates for innovative drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel therapeutic agents, particularly those targeting the central nervous system (CNS) and other specialized receptors.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs).
• Active Pharmaceutical Ingredient (API) Synthesis: Used in multi-step synthetic routes to construct complex molecules for preclinical and clinical development.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals requiring a functionalized tetrahydrobenzo[b]thiophene moiety.
• Contract Research & Manufacturing (CRAM): A valuable material for organizations providing custom synthesis and process development services.

Basic Information

Product Name	Methyl 2-Acetamido-4,5,6,7-Tetrahydrobenzo[B]Thiophene-3-Carboxylate
CAS No.	92539-89-4
Molecular Formula	C12H15NO3S
Molecular Weight	253.32 g/mol
Synonyms	Methyl 2-acetamido-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate; 2-Acetamido-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid methyl ester; 4,5,6,7-Tetrahydro-2-(acetylamino)benzo[b]thiophene-3-carboxylic acid methyl ester; Methyl 2-acetylamino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate; 92539-89-4; Tetrahydrobenzo[b]thiophene-3-carboxylate derivative
EINECS	Contact for details

Quality Control

Our Methyl 2-Acetamido-4,5,6,7-Tetrahydrobenzo[B]Thiophene-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.