Description

1-Isoquinolineacetic Acid,1,2,3,4-Tetrahydro-6-Methoxy-,Ethyl Ester is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex pharmacologically active molecules, particularly within the realm of central nervous system (CNS) research. Pharmaceutical R&D laboratories and fine chemical manufacturers need this high-purity intermediate to streamline their synthetic routes and accelerate drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel isoquinoline-based alkaloids and potential therapeutic agents targeting neurological pathways.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs) in CNS drug discovery.
• Fine Chemical Synthesis: Used in the multi-step synthesis of complex organic molecules requiring the tetrahydroisoquinoline core structure.
• Academic & Institutional R&D: Employed in university and research institute laboratories for studying heterocyclic chemistry and developing new synthetic methodologies.
• Reference Standard: Can be supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	1-Isoquinolineacetic Acid,1,2,3,4-Tetrahydro-6-Methoxy-,Ethyl Ester
CAS No.	92501-46-7
Molecular Formula	C₁₅H₁₉NO₃
Molecular Weight	261.32 g/mol
Synonyms	Ethyl 1,2,3,4-Tetrahydro-6-methoxy-1-isoquinolineacetate; 6-Methoxy-1,2,3,4-tetrahydroisoquinoline-1-acetic Acid Ethyl Ester; 1,2,3,4-Tetrahydro-6-methoxyisoquinoline-1-acetic Acid Ethyl Ester; (1,2,3,4-Tetrahydro-6-methoxy-1-isoquinolyl)acetic Acid Ethyl Ester; THIQ-6-OMe-OEt; 6-Methoxy-THIQ Ethyl Ester; Ethyl (1,2,3,4-Tetrahydro-6-methoxy-1-isoquinolyl)acetate
EINECS	Contact for details

Quality Control

Our 1-Isoquinolineacetic Acid,1,2,3,4-Tetrahydro-6-Methoxy-,Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our commitment to GMP-grade standards ensures the material is suitable for demanding research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled and stored accordingly to maintain stability. Keep away from strong bases and incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.