Description

D-Isovaline, 3-Mercapto-3-Methyl- (9Ci) is a specialized non-proteinogenic amino acid derivative featuring a unique thiol group, making it a valuable chiral building block and intermediate for advanced organic synthesis. Its structural motif is critical for research and development in creating novel compounds with specific biological or material properties. This high-purity intermediate is essential for pharmaceutical R&D, agrochemical synthesis, and advanced material science applications where precise stereochemistry and functional group manipulation are required.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for neurological and metabolic targets.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators that require specific stereochemistry for efficacy.
• Peptidomimetics & Bioactive Molecule Design: Acts as a constrained amino acid analog for constructing peptide mimics and modifying peptide backbones to enhance stability and biological activity.
• Ligand & Catalyst Development: Employed in the synthesis of chiral ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Biochemical Research: Utilized as a probe or standard in metabolic pathway studies and enzyme inhibition research due to its non-natural amino acid structure.
• Material Science Precursor: Functions as a monomer or functionalization agent in the synthesis of specialized polymers and smart materials.

Basic Information

Product Name	D-Isovaline, 3-Mercapto-3-Methyl- (9Ci)
CAS No.	92462-77-6
Molecular Formula	C6H11NO2S
Molecular Weight	161.22 g/mol
Synonyms	(2R)-2-Amino-3-mercapto-3-methylbutanoic acid; D-3-Mercapto-3-methylisovaline; (R)-2-Amino-3-mercapto-3-methylbutyric acid; (R)-3-Mercapto-3-methylisovaline; D-3-Methyl-3-mercaptoisovaline; 3-Mercapto-3-methyl-D-isovaline; 92462-77-6; (R)-2-Amino-3-(methylsulfanyl)-3-methylbutanoic acid (tautomer)
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and synthesis. Every batch is characterized using advanced analytical techniques to confirm identity, purity, and chiral integrity. Certificates of Analysis (COA) detailing specific results for assay, enantiomeric excess, and impurity profiles are available upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.