Description

5-(tert-Butyl)-1H-Indole is a versatile indole derivative characterized by a bulky tert-butyl substituent at the 5-position of the indole ring. This structural feature makes it a valuable advanced pharmaceutical intermediate and a crucial building block for the synthesis of complex organic molecules. It is primarily sought after by research institutions and fine chemical manufacturers engaged in drug discovery, agrochemical development, and materials science.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Building block for developing new-generation pesticides and herbicides with enhanced efficacy.
• Material Science Research: Used in the creation of organic semiconductors, ligands for catalysis, and specialty polymers.
• Chemical Research & Development: Serves as a standard or starting material in organic synthesis for constructing complex heterocyclic compounds.
• Ligand and Catalyst Design: The indole core can be functionalized to create novel ligands for metal-organic frameworks (MOFs) and catalytic systems.

Basic Information

Product Name	5-(tert-Butyl)-1H-Indole
CAS No.	92462-70-9
Molecular Formula	C₁₂H₁₅N
Molecular Weight	173.25 g/mol
Synonyms	5-tert-Butylindole; 5-(1,1-Dimethylethyl)-1H-indole; 1H-Indole, 5-(1,1-dimethylethyl)-; 5-tert-Butyl-1H-indole; 5-(tert-Butyl)indole; 5-t-Butylindole; 5-(tert-butyl)indole
EINECS	Contact for details

Quality Control

Our 5-(tert-Butyl)-1H-Indole is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing including HPLC for purity, GC for residual solvents, and NMR for structural confirmation to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.