Description

2,3,3A,4,5,6-Hexahydro-1H-Indolo[3,2,1-De][1,5]Naphthyridine Monohydrochloride is a complex heterocyclic organic compound supplied as a monohydrochloride salt. This high-purity intermediate is critical for pharmaceutical research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, particularly those targeting neurological and psychiatric disorders.
• Organic Synthesis Research: Valuable scaffold for medicinal chemists exploring structure-activity relationships (SAR) in new chemical entities.
• Reference Standard: Used as a certified reference material (CRM) for analytical method development and quality control in API manufacturing.
• Process Chemistry: Serves as a precursor in the scale-up and optimization of synthetic routes under current Good Manufacturing Practice (cGMP) guidelines.
• Biochemical Research: Investigated for its potential biological activity and receptor binding profiles in early-stage discovery programs.

Basic Information

Product Name	2,3,3A,4,5,6-Hexahydro-1H-Indolo[3,2,1-De][1,5]Naphthyridine Monohydrochloride
CAS No.	92446-57-6
Molecular Formula	C14H17ClN2
Molecular Weight	248.75 g/mol
Synonyms	1H-Indolo[3,2,1-de][1,5]naphthyridine, 2,3,3a,4,5,6-hexahydro-, monohydrochloride; Hexahydroindolonaphthyridine HCl; 1,2,3,4,5,6-Hexahydroindolo[3,2,1-de][1,5]naphthyridine hydrochloride; Indolonaphthyridine hydrochloride derivative; CAS 92446-57-6
EINECS	Contact for details

Quality Control

Our 2,3,3A,4,5,6-Hexahydro-1H-Indolo[3,2,1-De][1,5]Naphthyridine Monohydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.