Description

(E)-Methyl 5-(5-Bromothiophen-2-Yl)-3-Oxopent-4-Enoate is a high-purity, specialized organic intermediate featuring a brominated thiophene core and an α,β-unsaturated ester moiety. This compound is a critical building block in advanced organic synthesis, valued for its unique reactivity profile that enables the construction of complex molecular architectures. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, particularly in therapeutic areas targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging the thiophene heterocycle for bioactivity.
• Material Science Research: Serves as a precursor for conjugated polymers and organic electronic materials due to its electron-rich thiophene unit and polymerizable double bond.
• Chemical Biology Probes: Employed in the synthesis of labeled compounds and molecular probes for studying biological pathways and mechanisms.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	(E)-Methyl 5-(5-Bromothiophen-2-Yl)-3-Oxopent-4-Enoate
CAS No.	92364-23-3
Molecular Formula	C10H9BrO3S
Molecular Weight	289.15 g/mol
Synonyms	Methyl (2E)-5-(5-bromo-2-thienyl)-3-oxo-2-pentenoate; 5-(5-Bromothiophen-2-yl)-3-oxopent-4-enoic acid methyl ester; (E)-Methyl 5-(5-bromothiophen-2-yl)-3-oxopent-4-enoate; 2-Pentenoic acid, 5-(5-bromo-2-thienyl)-3-oxo-, methyl ester, (2E)-; Methyl 5-(5-bromothien-2-yl)-3-oxopent-4E-enoate
EINECS	Contact for details

Quality Control

Our (E)-Methyl 5-(5-Bromothiophen-2-Yl)-3-Oxopent-4-Enoate is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications and can provide necessary documentation for regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.