Description

[6As,(-)]-8β-Chloro-9α-Ethenyl-2,6,6Aα,7,8,9,10,10Aα-Octahydro-10α-Isothiocyanato-6,6,9-Trimethylnaphtho[1,2,3-Cd]Indole CAS NO 92219-96-0 is a complex, high-purity synthetic organic compound featuring a fused indole-naphthalene core structure with chloro, ethenyl, and isothiocyanato functional groups. This compound is of significant interest for advanced pharmaceutical research and development, particularly in the synthesis of novel bioactive molecules. It is primarily utilized by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, especially those targeting neurological or oncological pathways.
• Medicinal Chemistry Research: Used as a sophisticated scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Reference Standard: Employed as an analytical standard in method development and quality control for complex organic syntheses.
• Process Chemistry Development: Acts as a model compound for optimizing synthetic routes, scaling up production, and developing purification protocols.
• Biochemical Probe Synthesis: Utilized in the creation of specialized probes for studying biological systems and enzyme interactions.
• Fine Chemical Synthesis: Functions as a precursor for other high-value, specialty chemicals with specific stereochemical and functional properties.

Basic Information

Product Name	[6As,(-)]-8β-Chloro-9α-Ethenyl-2,6,6Aα,7,8,9,10,10Aα-Octahydro-10α-Isothiocyanato-6,6,9-Trimethylnaphtho[1,2,3-Cd]Indole
CAS No.	92219-96-0
Molecular Formula	C22H25ClN2S
Molecular Weight	384.96 g/mol
Synonyms	(-)-8β-Chloro-9α-ethenyl-10α-isothiocyanato-6,6,9-trimethyl-2,3,6,6a,7,8,9,10,10a,10b-decahydronaphtho[1,2,3-cd]indole; 8β-Chloro-9α-ethenyl-10α-isothiocyanato-6,6,9-trimethyl-2,3,6,6a,7,8,9,10,10a,10b-decahydronaphtho[1,2,3-cd]indole; NSC 339579; 92219-96-0; (6aS,10aR,10bS)-8-Chloro-9-ethenyl-10-isothiocyanato-6,6,9-trimethyl-2,3,6a,7,8,9,10,10a,10b,11-decahydronaphtho[1,2,3-cd]indole
EINECS	Contact for details

Quality Control

Our [6As,(-)]-8β-Chloro-9α-Ethenyl-2,6,6Aα,7,8,9,10,10Aα-Octahydro-10α-Isothiocyanato-6,6,9-Trimethylnaphtho[1,2,3-Cd]Indole is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specific test results are provided with every shipment. We can support development projects with material meeting research-grade to cGMP standards as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The container should be kept in a well-ventilated area and protected from moisture. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.